Local fluid dynamics in patients with bifurcated coronary lesions undergoing percutaneous coronary interventions

Although the coronary arteries are uniformly exposed to systemic cardiovascular risk factors, atherosclerosis development has a non-random distribution, which follows local mechanical stresses including flow-related hemodynamic forces. Among these, wall shear stress plays an essential role and it represents major factor affecting distribution of in bifurcations. Furthermore, emerging body evidence suggests that factors such as low oscillating may facilitate in-stent restenosis stent thrombosis after successful drug-eluting implantation. Drug-eluting implantation gold standard for bifurcation interventions. In this specific setting interventions on bifurcated lesions, impact fluid dynamics is expected play constitutes substantial opportunity future technical improvement. present review, available data summarized regarding clinical outcome patients with lesions.